|
2.3.2 |
Use of
In Vivo and In Vitro Studies |
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|
|
|
2.7 |
Safety Pharmacology Core Battery |
|
|
2.7.1 Central Nervous
System |
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2.7.2 Cardiovascular
System |
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2.7.3 Respiratory System |
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2.8 |
Follow Up and Supplemental Safety Pharmacology
Studies |
|
|
2.8.1.1 Central Nervous
Systems - EEC, EMG, ECG |
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2.8.1.2 Cardiovascular
System - Cardiac Output, Left Ventricular Pressure |
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2.8.1.3 Respiratory
System - Pulmonary Arterial Pressure |
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2.8.2.1 Renal/Urinary
System - Renal Blood Flow |
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|
2.8.2.2 Autonomic
Nervous System - Baroreflex, Heart Rate Variability |
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|
2.8.2.3 Gastrointestinal
System - Transit Time, Gut Motility |
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2.11 |
Application of Good Laboratory Practice (GLP) |
